eTOC Series Applications

Online Measurement of Ultra-Pure Water using TOC-1000e

When used in the pharmaceutical and semiconductor industries, it is important to continuously monitor the quality of pure water to keep impurities on a low level. For optimum quality control in pure water, the Online Total Organic Carbon Analyzer eTOC (TOC-1000e) enables highly sensitive analysis at detection limits as low as 0,1 µg/L based on the UV oxidation-conductivity measurement method. This application note introduces an example of online measurement of ultra-pure water using eTOC.



TOC System Suitability Test Using TOC-1000e according to USP 643

For water used in the production of pharmaceuticals, the US Pharmacopoeia (USP) specifies that total organic carbon (TOC) should be used for management of organic impurities. According to USP <643>, TOC analyzers to be used for analysis of bulk purified water and water for injection must satisfy the TOC system suitability test, using standard solutions with a carbon content of 0,500 mg/L. This application note introduces an actual example of TOC system suitability testing using the online total organic carbon analyzer TOC-1000e and optional sampler.




Other TOC analysers


Highly-advanced Online TOC analyser, used in a wide range of water analysis applications 


Laboratory TOC analyser utilizing the high temperature/catalytic combustion oxidation method


Laboratory wet-chemical TOC analyser utilizing the UV/Persulfate oxidation method


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